Preliminary screening of secondary metabolites isolated from marine macro algae and its bactericidal activity against s.typhi

Thamizharasan S

The aim of the study was to evaluate the antibacterial activity of the extracts of medicinal marine algal plant Padina gymnosphora against Salmonella typhi, a gastro intestinal bacterial strain. The plant was selected on the basis of the previous study report on ethnobotanical uses. Aqueous and methanol extracts of the plant was screened in vitro for their antibacterial activity against the gastro intestinal bacteria Salmonella typhi. 100μl concentrations of both extracts were used in well diffusion assay. The study showed the anti-bacterial effect, both in methanol and aqueous extracts.The growth inhibition rate of Salmonella typhi was 14mm in aqueous extract. But the inhibitory zone of methanol extract was seen above 26mm. The standard antibiotics show the inhibition zone as 29mm.The methanol extracts of plant was more efficient as compared to the aqueous extract.

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