“The effects of variation in the time of planting of artemisia annua on accumulation of artemisinin content in goalpara district of assam”

Gunamoni Das and R.K. Sharma

The Chinese herb Artemisia annua L. belong to the family Asteraceae produces artemisinin are used worldwide as drugs against malaria. Chloroquine and replacement drugs have lost effectiveness with the development of resistance and have increasingly been replaced by derivatives of artemisinin combined with other drugs known as artemisinin–based combination therapies (ACTs), they provide the most effective treatment at present. In India, interest in cultivating Artemisia annua resulted in emerging industrial activities demanding local biomass with high content of artemisinin to start new production chains. Several field crop experiments were carried out on the anti-malarial medicinal plant Artemisia annua over four cropping periods. Results were obtained after 25 months field study carried out in some areas of Goalpara district of Assam. The experiments examined the effects of variation in the time of planting and number of harvests on the yield of artemisinin and plant growth and development characters related to it. The observations showed that the artemisinin yield was positively correlated with leaf yield and number of harvests. High yields of artemisinin were realized when crop produced artemisinin-rich leaves accompanied by least possible growth of stem tissue, attained by 2 times harvesting of full grown crops.

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